Article

Motor and cognitive disorders in cerebellar disease. Clinical signs of cerebellar ataxia include ataxia of stance and gait, truncal and limb ataxia as well as dysarthria and oculomotor signs. Lesions of the flocculonodular lobe and caudal vermis are followed by truncal ataxia and oculomotor signs, lesions of the rostral vermis by ataxia of stance and gait, and lesions of cerebellar hemisphere by ipsilateral limb ataxia. Lesions of the superior paravermal cerebellum are accompanied by dysarthria. Clinical signs of ataxia are a consequence of cerebellar incoordination of movement which is caused by disordered timing and control of forces or torques at and across joints. Part of the clinical picture of cerebellar ataxia is likely explained also by disorders in motor learning, in particular in adaptation and lack of automatization of movement. More recent anatomical data and findings in human lesion and brain imaging studies suggest a possible additional role of the cerebellum in non-motor functions, i.e. Cognition. The right posterolateral cerebellar hemisphere is thought to be involved in language, the left posterolateral hemisphere in visuomotor tasks and the vermis in affect and behavior. At present, it is unclear whether cognitive dysfunction should be considered part of the clinical picture of cerebellar disease. Cerebellar disorders, in any case, do not present with prominent cognitive dysfunction.

Langue : ALLEMAND

Tiré à part : OUI