Article

Objectives: To describe the efficacy of intrathecal baclofen (ITB) therapy in the management of spasticity in young children with cerebral palsy (CP) and to identify risk factors for complications. Design: Consecutive case series of 25 implanted ITB delivery systems during a 48-month period. Setting: Pediatric specialty hospital and outpatient department. Participants: Twenty-three children (age range, 4.5-17.4y) with CP (spastic diplegia in 22%; spastic quadriplegia in 61%; mixed-type diplegia in 4%; mixed-type quadriplegia in 13%). Intervention: Intrathecal baclofen therapy in children with cerebral palsy.
Main Outcome Measures: Ashworth Scale scores before treatment and at 6 and 12 months after ITB therapy; frequency and nature of complications; and relation between patient characteristics and outcomes. Results: Average Ashworth scores standard deviation decreased from 3.26+/-.73 to 2.34+/-.83 (Pless than or equal to.01) in the lower extremities and from 2.69+/-.79 to 2.00+/-.55 (Pless than or equal to.05) in the upper extremities 6 months after ITB therapy and remained comparably decreased at 12 months. Explantation was required in 44% (11/25), with wound complications as the leading cause in 73% (8/11). Complications were associated with the diagnosis of mixed-type CP, as compared with pure spastic types (Pless than or equal to5.01). Trends suggest that children of smaller size and younger age, as well as those with gastrostomy tubes and nonambulatory status, were more likely to encounter complications necessitating explantation. Conclusion: ITB therapy effectively reduced spasticity in children with CP. However, complications necessitating explantation can occur. Further research is needed to identify criteria describing the ideal pediatric candidate for ITB. (C) 2002 by the American Congress of Rehabilitation Medicine and the American Academy of Physical Medicine and Rehabilitation.

Langue : ANGLAIS

Identifiant basis : 2003225567