Article

The aim of this study was to assess cognitive function at the age of 19 years
in individuals of very low birthweight (VLBW; </=1500g) and in term-born
comparison individuals.
Method In this hospital-based follow-up study, 55 VLBW
participants (30 males, 25 females; mean birthweight 1217g, SD 233g; mean
gestational age 29.1wks, SD 2.5wks) and 81 comparison individuals (42 males, 39
females; mean birthweight 3707g, SD 433g; mean gestational age 39.7wks, SD
1.2wks) were examined with a standardized IQ test (Wechsler Adult Intelligence
Scale III) to assess general cognitive ability.
Results Over half (53%) of the
VLBW participants achieved a low IQ score (defined as >1SD below the mean in the
comparison group; odds ratio 6.4 vs comparison individuals; 95% confidence
interval 2.8-14.4; p<0.001). None of the VLBW group, compared with 22% of the
comparison individuals, achieved a high IQ score (>1SD above the comparison
mean). VLBW participants scored lower than comparison individuals on full,
verbal, and performance IQ, as well as on all four indices (p</=0.001). The
subtest profile indicated problems on all subtests, but especially on those
related to arithmetic and visual-perceptual tasks. Interpretations Few studies
have undertaken a comprehensive assessment of general cognitive outcome (IQ)
among young adults of VLBW. Our results indicate that VLBW seems to have a global
and lasting impact on cognitive ability. Full-scale IQ assessment may reveal
important learning problems in young adults of VLBW, and should be performed to
inform appropriate assistance to enhance academic achievement and the chances of permanent employment as adults.
CI - (c) The Authors. Journal compilation (c) Mac Keith Press 2010.

Langue : ANGLAIS