Article

Genomics and its related fields have expanded rapidly, primarily because of the
potential utility for clinical decision making and improving our understanding of
the pathophysiology of complex conditions. The state of the science and
technology associated with this field is such that current and future health care
providers, when consulting with new patients about their acquired brain injury
and options for rehabilitation, will use genetic information as a routine part of
the process, which may include information received from a laboratory report that
uses transcriptomic data, informs regarding patient prognosis,
and makes
recommendations for individualized therapeutic approaches to optimize recovery.
This may sound like science fiction, but, in the field of oncology, it is the
norm for breast cancer and, more recently, for colon cancer, with expansion to
other types of cancer on the horizon as research data continue to contribute to
the understanding of the pathophysiology of these conditions. Something similar
for rehabilitation after acquired brain injury is much further off on the
horizon. However, it is a possibility that will never be realized if the
community of scientists and health care providers who work with these patients do
not have the knowledge or expertise to embrace genomics and related approaches.
This article discusses these approaches, some practical considerations for using
such approaches, and what is currently published in this area with regard to
brain injury.
CI - Copyright (c) 2011 American Academy of Physical Medicine and Rehabilitation.
Published by Elsevier Inc. All rights reserved.

Langue : ANGLAIS