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Efficiency of bone density testing by dual-biphotonic X-rays absorptiometry for diagnosis of osteoporosis according to French guideline recommendations : the
PRESAGE study

GUGGENBUHL P; DUFOUR R; LIU LEAGE S; SAPIN H; CORTET B
JOINT BONE SPINE , 2011, vol. 78, n° 5, p. 493-498
Doc n°: 153754
Localisation : Accès réservé

D.O.I. : http://dx.doi.org/DOI:10.1016/j.jbspin.2010.12.009
Descripteurs : DA535 - OSTEOPOROSE

Bone mineral density is a major risk factor of fracture.
Its measurement is reimbursed by French national health insurance according to
clinical criteria. In this multicentre cross-sectional observational study, we
estimated the proportion of postmenopausal women with osteoporosis among those
referred for a bone mineral density measurement. Risk factors for osteoporosis
and therapeutic recommendations were described. RESULTS: Six hundred and
forty-six postmenopausal women were evaluated. Osteoporosis was diagnosed in
57.6%, osteopenia in 38.7% and a normal bone mineral density in 3.7%. The main
risk factors for fracture were personal history of fracture (40%), family
fracture (23%), smoking (15%) and glucocorticoids use (15%). Anti-osteoporosis
drug was recommended for 93% of women with osteoporosis and for 45% of women with
osteopenia. A logistic regression analysis showed that a T-score=-2.5 was the
most important factor related to the treatment decision-making. Cluster analysis
identified five types of women with different combinations of fracture risk
factors. The percentage of postmenopausal women -96.3% - referred for bone
mineral density and for whom a treatment could be recommended had osteoporosis or
osteopenia. CONCLUSION: In spite of recommendations, the physician therapeutic
decision-making was mainly based on the bone mineral density result.
CI - Copyright (c) 2011 Societe francaise de rhumatologie. Published by Elsevier SAS.
All rights reserved.

Langue : ANGLAIS

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