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Anxiety in adolescents born preterm or with very low birthweight

SOMHOVD MJ; HANSEN BM; BROK J; ESBJORN BH; GREISEN G
DEV MED CHILD NEUROL , 2012, vol. 54, n° 11, p. 988-994
Doc n°: 160891
Localisation : Documentation IRR

D.O.I. : http://dx.doi.org/DOI:10.1111/j.1469-8749.2012.04407.x
Descripteurs : AJ1 - ETUDES GENERALES - NEUROLOGIE INFANTILE

AIM: To determine if adolescents who are born very preterm (<32 wks; of
gestation) and/or with very low birthweight (VLBW; <1500 g) have a higher risk of
experiencing clinically significant anxiety problems. METHOD: We used a
systematic review and meta-analysis. We searched the databases ISI Web of
Knowledge, PubMed, PsycNET, Educational Resources Information Center (ERIC),
Latin American and Caribbean Literature on the Health Sciences (LILACS), and
Virtual Health Library (VHL) with equivalent search expressions (from the
databases' inception to June 2011). Also, we screened reference lists of
identified articles. We selected case-control studies of adolescents 11 to 20
years old who were very preterm/VLBW and had a matched reference group born at
term with normal birthweight that reported a validated anxiety outcome measure.
For data extraction, two authors independently reviewed titles, abstracts, and
full articles identified through the searches. Subsequently two authors
independently extracted data. RESULTS: We included six studies with 1519
adolescents (787 very preterm/VLBW, 732 comparisons). The general risk of
developing clinically significant anxiety problems was nearly doubled (p<0.05) in
the very preterm/VLBW population (OR 2.27, 95% confidence interval 1.15-4.47).
The overall prevalences were 9.9% in the very preterm/VLBW group and 5.5% in the
comparison group. INTERPRETATION: Those born very preterm/VLBW have an increased
risk of developing clinically significant anxiety problems in adolescence.
CI - (c) The Authors. Developmental Medicine & Child Neurology (c) 2012 Mac Keith
Press.

Langue : ANGLAIS

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