Article

General developmental outcome is known to be good in school-aged children
who experienced febrile seizures. We examined cognitive and behavioural outcomes
in preschool children with febrile seizures, including language and executive
functioning outcomes. METHOD: This work was performed in the Generation R Study,
a population-based cohort study in Rotterdam from early fetal life onwards.
Information about the occurrence of febrile seizures was collected by
questionnaires at the ages of 1, 2, and 3 years. At the age of 3 years, behaviour
and emotion were assessed using the Child Behavior Checklist. Information on
expressive language development was obtained by the Language Development Survey
at the age of 2 years 6 months. To assess executive functioning, parents
completed the Behaviour Rating Inventory of Executive Function - Preschool
Version when their children were 4 years old. Final analyses were based on 3157
children. RESULTS: No associations were found between febrile seizures and the
risk of behavioural problems or executive functioning. In contrast to single
febrile seizures, recurrent febrile seizures were significantly associated with
an increased risk of delayed vocabulary development (odds ratio 3.22, [95%
confidence interval 1.30-7.94]). INTERPRETATION:
Febrile seizures are not
associated with problem behaviour or executive functioning in preschool children,
but the results suggest that children with recurrent febrile seizures might be at
risk for delayed language development.
CI - (c) The Authors. Developmental Medicine & Child Neurology (c) 2012 Mac Keith
Press.

Langue : ANGLAIS