Article

While acute rehabilitation following neurotrauma has evolved over the
past 30 years to include the common use of pharmacologic agents to promote
synaptogenesis and improve recovery potential, little guidance exists for a
similar strategy in the post-acute or community re-entry phases of injury.
Drawing upon the existing scientific literature, models of pharmacologic
intervention in promoting stability in other disease states and the authors'
collective clinical experience, this article provides a potential structure by
which to implement methods to create a stable physiologic platform to facilitate
behavioral intervention. OBJECTIVES: This article reviews basic foundations for
physiologic optimization, pharmacologic strategies for facilitation, and
dyscompliance after neurotrauma. METHODS: Literature review, case analysis,
clinical experience.
RESULTS: Guidelines for facilitation of behavioral
intervention with physiologic stabilization and with pharmacologic agents are
presented with clinical rationale for their utilization. CONCLUSIONS: Improving
physiologic readiness for behavioral intervention in the post-acute and community
re-entry phases following neurotrauma has potential to improve both the efficiency and durability of these efforts.

Langue : ANGLAIS