Article

OBJECTIVE: To identify the most commonly used patient-reported outcome (PRO)
measures in clinical vestibular research, and to assess their test
characteristics and applicability to the study of age-related vestibular loss in
clinical trials. DATA SOURCES: We performed a systematic review of the PubMed,
Cumulative Index to Nursing and Allied Health Literature, and PsycINFO databases
from 1950 to August 13, 2013. STUDY SELECTION: PRO measures were defined as
outcomes that capture the subjective experience of the patient (eg, symptoms,
functional status, health perceptions, quality of life). Two independent
reviewers selected studies that used PRO measures in clinical vestibular
research. Disparities were resolved with consensus between the reviewers. Of 2260
articles initially found in the literature search, 255 full-text articles were
retrieved for assessment. Of these, 104 met inclusion criteria for data
collection. DATA EXTRACTION: PRO measures were identified by 2 independent
reviewers. The 4 most commonly used PROs were evaluated for their applicability
to the condition of age-related vestibular loss. Specifically, for these 4 PROs,
data were collected pertaining to instrument test-retest reliability, item
domains, and target population of the instrument. DATA SYNTHESIS: A total of 50
PRO instruments were identified. The 4 most frequently used PROs were the
Dizziness Handicap Inventory, Activities-specific Balance Confidence scale,
Vertigo Symptom Scale-short form, and visual analog scale. Of these 4 PROs, 3
were validated for use in patients with vestibular disease and 1 was validated in
community-dwelling older individuals with balance impairments. Items across the 4
PROs were categorized into 3 domains based on the International Classification of
Functioning, Disability and Health: activity, participation, and body functions
and structures. CONCLUSIONS: None of the most commonly used PRO instruments were
validated for use in community-dwelling older adults with age-related vestibular
loss. Nevertheless, the 3 common domains of items identified across these 4 PRO
instruments may be generalizable to older adults and provide a basis for
developing a PRO instrument designed to evaluate the effectiveness of
interventions targeted toward age-related vestibular loss.
CI - Copyright (c) 2015 American Congress of Rehabilitation Medicine. Published by
Elsevier Inc. All rights reserved.

Langue : ANGLAIS