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Tailoring Brain Stimulation to the Nature of Rehabilitative Therapies in Stroke : A Conceptual Framework Based on their Unique Mechanisms of Recovery

Despite showing early promise, several recent clinical trials of noninvasive
brain stimulation (NIBS) failed to augment rehabilitative outcomes of the paretic
upper limb. This article addresses why pairing NIBS with unilateral approaches is
weakly generalizable to patients in all ranges of impairments.
The article also
addresses whether alternate therapies are better suited for the more impaired
patients, where they may be more feasible and offer neurophysiologic advantages
not offered with unilateral therapies. The article concludes by providing insight
on how to create NIBS paradigms that are tailored to distinctly augment the
effects of therapies across patients with varying degrees of impairment.
CI - Copyright (c) 2015 Elsevier Inc. All rights reserved.

Langue : ANGLAIS

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