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Traumatic Brain Injury-Practice Based Evidence Study : Design and Patients, Centers, Treatments and Outcomes

Article consultable sur : http://www.archives-pmr.org

OBJECTIVES: To describe study design, patients, centers, treatments, and outcomes
of a traumatic brain injury (TBI) practice-based evidence (PBE) study and to
evaluate the generalizability of the findings to the U.S. TBI inpatient
rehabilitation population. DESIGN: Prospective, longitudinal, observational
study. SETTING: Ten inpatient rehabilitation centers. PARTICIPANTS: Patients
(N=2130) enrolled between October 2008 and September 2011 and admitted for
inpatient rehabilitation after an index TBI injury. INTERVENTIONS:
Not applicable. MAIN OUTCOME MEASURES: Return to acute care during rehabilitation,
rehabilitation length of stay,
FIM at discharge, residence at discharge, and 9
months postdischarge rehospitalization, FIM, participation, and subjective
well-being. RESULTS: The level of admission FIM cognitive score was found to
create relatively homogeneous subgroups for the subsequent analysis of best
treatment combinations. There were significant differences in patient and injury
characteristics, treatments, rehabilitation course, and outcomes by admission FIM
cognitive subgroups. TBI-PBE study patients were overall similar to U.S. national
TBI inpatient rehabilitation populations. CONCLUSIONS: This TBI-PBE study
succeeded in capturing naturally occurring variation in patients and treatments,
offering opportunities to study best treatments for specific patient impairments.
Subsequent articles in this issue report differences between patients and
treatments and associations with outcomes in greater detail.
CI - Copyright (c) 2015 American Congress of Rehabilitation Medicine. Published by
Elsevier Inc. All rights reserved.

Langue : ANGLAIS

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