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Cancer-Related Fatigue : Persistent, Pervasive, and Problematic

GERBER LH
PHYS MED REHABIL CLIN N AM , 2017, vol. 28, n° 1, p. 65-88
Doc n°: 181199
Localisation : Documentation IRR

D.O.I. : http://dx.doi.org/DOI:10.1016/j.pmr.2016.08.004
Descripteurs : MB - CANCEROLOGIE

Cancer-related fatigue (CRF) is commonly reported by patients with cancer before,
during, and after treatment. It is a persistent sense of tiredness that
interferes with function, is distressing, and requires monitoring and, possibly,
treatment. Fatigue assessment requires objective measures and self-reports, such
as Functional Assessment of Cancer Therapy-Fatigue. Significant contributors to
CRF include anemia, pain, insomnia, depressive symptoms, and elevated BMI.
Elevated inflammatory cytokines, diabetes mellitus, cortisol, and cellular
dysregulation have been associated with CRF. None is causal. Effective treatments
include correction of other medical problems, especially anemia, cognitive
behavioral therapy, exercise, modafinil, and corticosteroids for short-term use.
CI - Copyright A(c) 2016 Elsevier Inc. All rights reserved.

Langue : ANGLAIS

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