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Evaluation of muscle strength and manual dexterity in patients with Charcot-Marie-Tooth disease

KOBESOVA A; NYVLTOVA M; KRAUS J; KOLAR P; SARDINA A; MAZANEC R; ANDEL R
J HAND THER , 2016, vol. 29, n° 1, p. 66-72
Doc n°: 181823
Localisation : Documentation IRR

D.O.I. : http://dx.doi.org/DOI:10.1016/j.jht.2015.12.002
Descripteurs : AC24 - POLYNEUROPATHIES

Differences in hand-muscle
strength/dexterity between dominant (DH) and non-dominant (NDH) hand in
Charcot-Marie-Tooth disease (CMT) are not well understood. PURPOSE OF THE STUDY:
To compare muscle strength/dexterity between DH and NDH and to correlate manual
dexterity, strength and sensory function. METHODS: Thirty CMT
patients were studied using functional muscle testing (FMT) and strength
(dynamometry), dexterity (the Nine Hole Peg Test [NHPT]), and Jebsen-Taylor Hand
Function [JTT]), and sensory function (the Nottingham Sensory Assessment [NSA]).
RESULTS: Scores were worse for DH than NDH on FMT (p = 0.043) and NHPT (p =
0.014) but not on JTT (p = 0.098), handgrip strength (p = 0.710) or tripod pinch
(p = 0.645). NSA did not correlate significantly with any tests (p's0.05).
CONCLUSIONS: In CMT disease, DH appears more impaired than NDH in terms of
function and dexterity. Greater muscle weakness in DH may also emerge as CMT progresses. LEVEL OF EVIDENCE: 3b.
CI - Copyright (c) 2016 Hanley & Belfus. Published by Elsevier Inc. All rights reserved.

Langue : ANGLAIS

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