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Are the average gait speeds during the 10meter and 6minute walk tests redundant in Parkinson disease ?

We investigated the relationships between average gait speed collected with the
10Meter Walk Test (Comfortable and Fast) and 6Minute Walk Test (6MWT) in 346
people with Parkinson disease (PD) and how the relationships change with
increasing disease severity. Pearson correlation and linear regression analyses
determined relationships between 10Meter Walk Test and 6MWT gait speed values for
the entire sample and for sub-samples stratified by Hoehn & Yahr (H&Y) stage I
(n=53), II (n=141), III (n=135) and IV (n=17). We hypothesized that redundant
tests would be highly and significantly correlated (i.e. r>0.70, p<0.05) and
would have a linear regression model slope of 1 and intercept of 0. For the
entire sample, 6MWT gait speed was significantly (p<0.001) related to the
Comfortable 10 Meter Walk Test (r=0.75) and Fast 10Meter Walk Test (r=0.79) gait
speed, with 56% and 62% of the variance in 6MWT gait speed explained,
respectively. The regression model of 6MWT gait speed predicted by Comfortable 10
Meter Walk gait speed produced slope and intercept values near 1 and 0,
respectively, especially for participants in H&Y stages II-IV. In contrast, slope
and intercept values were further from 1 and 0, respectively, for the Fast
10Meter Walk Test. Comfortable 10 Meter Walk Test and 6MWT gait speeds appeared
to be redundant in people with moderate to severe PD, suggesting the Comfortable
10 Meter Walk Test can be used to estimate 6MWT distance in this population.
CI - Copyright (c) 2016 Elsevier B.V. All rights reserved.

Langue : ANGLAIS

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