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Subthalamic nucleus stimulation and gait in Parkinson's Disease : a not always fruitful relationship

COSSU G; PAU M
GAIT POSTURE , 2017, vol. 52, p. 205-210
Doc n°: 183588
Localisation : Documentation IRR

D.O.I. : http://dx.doi.org/DOI:10.1016/j.gaitpost.2016.11.039
Descripteurs : AF5 - PARKINSON, DF234 -TROUBLES DE LA MARCHE DANS LES AUTRES PATHOLOGIES NEUROLOGIQUES

Deep brain stimulation (DBS) of the subthalamic nucleus (STN) provides efficient
treatment for the alleviation of motor signs in patients with advanced
Parkinson's disease (PD),
but its specific effects on gait is sometimes less
successful as it may even lead to an aggravation of freezing of gait. To better
understand when axial symptoms can be expected to improve and when they may
worsen or be resistant to STN-DBS, we propose here a narrative review that
considers the recent literature evidences based on instrumental gait analysis
data. Our aim is to report about the efficacy of STN-DBS on PD gait, analyzing
the clinical and procedural factors involved, and discussing the strategies for
optimizing such effectiveness in patients with advanced PD.
CI - Copyright (c) 2016 Elsevier B.V. All rights reserved.

Langue : ANGLAIS

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