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Chronic pain, fatigue, and depressive symptoms in adults with spastic bilateral cerebral palsy

Aim To investigate the prevalence and co-occurrence of chronic pain, fatigue, and
depressive symptoms in adults with spastic bilateral cerebral palsy (SBCP) and
explore associations of chronic pain and fatigue with depressive symptoms and
daily functioning. Method Fifty-six adults with SBCP without severe cognitive
impairment participated (35 males, 21 females; mean age 36y 5mo, SD 5y 10mo;
Gross Motor Function Classification System level I [13], II [28], III [11], IV
[4]). Chronic pain (>3mo), severity and nature of fatigue (Fatigue Severity
Scale; Multidimensional Fatigue Inventory), and depressive symptoms (Center for
Epidemiological Studies Depression Scale) were assessed. Associations were
explored using multivariable logistic regression analyses. Results The study
sample had a higher prevalence of chronic pain (75% vs 39%; p<0.001), mean
fatigue (Fatigue Severity Scale, 4.4 [SD 1.3] vs 2.9 [SD 1.1]; p<0.001), and
prevalence of depressive symptoms (25% vs 12%; p=0.004) than Dutch healthy
reference samples. Chronic pain and severe fatigue co-occurred in 34% and in
combination with depressive symptoms in 16% of the participants. Severity of
fatigue was associated with depressive symptoms (OR 3.38; p<0.01). Chronic pain
and fatigue were not associated with limitations in daily functioning.
Interpretation These findings suggest that adults with SBCP are severely affected
by chronic pain, fatigue, and depressive symptoms, in addition to their spastic
paresis.
CI - (c) The Authors. Developmental Medicine & Child Neurology (c) 2012 Mac Keith
Press.

Langue : ANGLAIS

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