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Effects of Dopamine on Motor Recovery and Training in Adults and Children With Nonprogressive Neurological Injuries: A Systematic Review

BRADLEY C; DAMIANO DL
NEUROREHABIL NEURAL REPAIR , 2019, vol. 33, n° 5, p. 331-344
Doc n°: 189667
Localisation : Centre de Réadaptation de Lay St Christophe

D.O.I. : https://doi.org/10.1177%2F1545968319837289
Descripteurs : AF12 - PATHOLOGIQUE

The strong link between dopamine and motor learning has been well-established in the animal literature with similar findings reported in healthy adults and the elderly. Objective. We aimed to conduct the first, to our knowledge, systematic review of the literature on the evidence for the effects of dopaminergic medications or genetic variations in dopamine transmission on motor recovery or learning after a nonprogressive neurological injury. Methods. A PubMed search was conducted up until April 2018 for all English articles including participants with nonprogressive neurological injury such as cerebral palsy, stroke, spinal cord injury, and traumatic brain injury; quantitative motor outcomes; and assessments of the dopaminergic system or medications

levodopa, dopamine agonists, neurological rehabilitation, genetic variation

Langue : ANGLAIS

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