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Neuronavigated high-frequency repetitive transcranial magnetic stimulation for chronic post-stroke dysphagia

There are potential benefits of repetitive transcranial magnetic
stimulation (rTMS) in improving swallowing functions after stroke; however, few
studies have been performed in the chronic stroke population. This study aims to
distil the key effects of rTMS on swallowing functions and swallowing-related
quality of life. METHODS: Twenty-two participants with chronic post-stroke
dysphagia were randomly assigned into active or sham rTMS groups. Seven
participants withdrew from the study, thus data from 15 participants (mean age
64.6 years) were analysed. Participants received 3,000 pulses of 5 Hz rTMS
(active: n = 11; sham: n = 4) on the tongue area of the motor cortex for 10 days
over a period of 2 weeks. All participants were assessed 1 week before, and 2
months, 6 months and 12 months after stimulation. Outcomes were measured by a
videofluoroscopic swallowing study, swallowing-related quality-of-life
questionnaire and Iowa Oral Performance Instrument. RESULTS: No statistically
significant effects were identified for any outcome measures. CONCLUSION: This
study indicates that 5 Hz rTMS applied over the tongue area of the motor cortex
is not effective for improving swallowing function in individuals with chronic
post-stroke dysphagia. Possible explanations for these non-significant results
are dis cussed. Future studies should explore the potential of the current
protocol in conjunction with conventional dysphagia therapy.

Langue : ANGLAIS

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