Article

OBJECTIVES: To characterize the spasticity and range of motion (ROM) in patients
with hereditary spastic paraplegia (HSP) and to correlate these parameters with
walking speed. DESIGN: An observational population-based cohort study. SETTING:
Patient data were acquired from a population-based epidemiologic study performed
earlier in Estonia. PARTICIPANTS: Persons (N=46) (mean age, 50.1y) with
clinically confirmed HSP diagnosis (mean duration, 20.9y) participated in the
study. INTERVENTIONS: Active and passive ROMs were measured with a plastic 360
degrees goniometer. Spasticity was evaluated by using the modified Ashworth scale
(MAS). The time it took a patient to walk 10m was recorded. MAIN OUTCOME
MEASURES: Measurements included testing of active and passive ROM as a marker for
mobility, the MAS for spasticity, and time to complete a 10-m walk. RESULTS: A
higher degree of spasticity in hip muscles was associated with lower values of
active ROM and slower walking. Walking speed was negatively correlated to disease
duration and participant age. CONCLUSIONS: The present study provides analysis of
the contributions of spasticity and ROM to walking speed in HSP, both factors
negatively influence gait in persons with HSP.

Langue : ANGLAIS