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Functional performance and inflammatory cytokines after squat exercises and whole-body vibration in elderly individuals with knee osteoarthritis

Article consultable sur : http://www.archives-pmr.org

OBJECTIVE: To investigate the effects of squat exercises combined with whole-body
vibration on the plasma concentration of inflammatory markers and the functional
performance of elderly individuals with knee osteoarthritis (OA). DESIGN:
Clinical, prospective, randomized, single-blinded study.
SETTING: Exercise
physiology laboratory. PARTICIPANTS: Elderly subjects with knee OA (N=32) were
divided into 3 groups: (1) squat exercises on a vibratory platform (platform
group, n=11); (2) squat exercises without vibration (squat group, n=10); and (3)
the control group (n=11). INTERVENTIONS: The structured program of squat
exercises in the platform and squat groups was conducted 3 times per week, on
alternate days, for 12 weeks. MAIN OUTCOME MEASURES: Plasma soluble tumor
necrosis factor-alpha receptors 1 (sTNFR1) and 2 (sTNFR2) were measured using
immunoassays (the enzyme-linked immunosorbent assay method). The Western Ontario
and McMaster Universities Osteoarthritis Index questionnaire was used to evaluate
self-reported physical function, pain, and stiffness. The 6-minute walk test, the
Berg Balance Scale, and gait speed were used to evaluate physical function.
RESULTS: In the platform group, there were significant reductions in the plasma
concentrations of the inflammatory markers sTNFR1 and sTNFR2 (P<.001 and P<.05,
respectively) and self-reported pain (P<.05) compared with the control group, and
there was an increase in balance (P<.05) and speed and distance walked (P<.05 and
P<.001, respectively). In addition, the platform group walked faster than the
squat group (P<.01). CONCLUSIONS: The results suggest that whole-body vibration
training improves self-perception of pain, balance, gait quality, and
inflammatory markers in elderly subjects with knee OA.
CI - Copyright (c) 2012 American Congress of Rehabilitation Medicine. Published by
Elsevier Inc. All rights reserved.

Langue : ANGLAIS

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