Article

Evaluation of the clinical effectiveness and safety of a new
custom-made valgus knee brace (OdrA) in medial knee osteoarthritis (OA) in terms
of pain and secondary symptoms. METHODS: Open-label prospective study of patients
with symptomatic medial knee OA with clinical evaluation at 6 and 52 weeks (W6,
W52). We systematically assessed pain on a visual analog scale (VAS), Knee injury
and Osteoarthritis Outcome Score (KOOS), spatio-temporal gait variables, use of
nonsteroidal anti-inflammatory drugs (NSAIDs) and analgesic-sparing effects of
the brace and tolerance. Mean scores were compared at baseline, W6 and W52 and
the effect size (ES) and 95% confidence intervals (95% CIs) were calculated.
RESULTS: We included 20 patients with knee OA (mean age 64.2+/-10.2 years, mean
body mass index 27.2+/-5.4kg/m(2)). VAS pain and KOOS were improved at W6 and
W52: pain (ES=0.9 at 1 year), amelioration of other symptoms (ES=0.4), and
function in activities of daily living (ES=1.1), sports and leisure (ES=1.5),
quality of life (ES=0.9) and gait speed (ES=0.41). In total, 76% of patients
showed clinical improvement at 1 year. Analgesic and NSAIDs consumption was
significantly decreased at W6 and W52. One serious adverse effect noted was
lower-limb varices, and observance was deemed satisfactory at 1 year. CONCLUSION:
This new unloader brace appeared to have good effect on medial knee OA, with an
acceptable safety profile and good patient compliance.
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Langue : ANGLAIS