Article

OBJECTIVE: To provide a quantitative synthesis of randomized controlled trials
(RCTs) examining the effect of exercise training on muscular and
cardiorespiratory fitness in persons with multiple sclerosis (MS). DATA SOURCES:
Three electronic databases, PubMed, Google Scholar, and Web of Science, were
searched for all relevant articles published up until October 2014. STUDY SELECTION: Keywords included exercise or aerobic or strength or resistance
training or cardiorespiratory and multiple sclerosis.
Trials examining the effect
of exercise training on muscular and/or cardiorespiratory fitness parameters were
included. DATA EXTRACTION: The initial search yielded 1501 articles; of these, 62
were reviewed in detail, and 20 RCTs met the inclusion criteria and provided
enough data to compute effect sizes (ESs) (Cohen d).
The meta-analyses was
conducted using a random effects model to compute the overall or mean ES per
fitness parameter. DATA SYNTHESIS: The mean ES was .27 (SE=.05; 95% confidence
interval [CI], .17-.38; z=5.05;
P<.001) for muscular fitness outcomes and .47
(SE=.09; 95% CI, .30-.65; z=5.4; P<.001) for cardiorespiratory fitness outcomes.
The weighted mean ES was not heterogeneous for muscular (Q13=11.09, P=.60,
I(2)=.00) or cardiorespiratory (Q9=7.83, P=.55, I(2)=.00) fitness outcomes.
CONCLUSIONS: The cumulative evidence supports that exercise training is
associated with changes in muscular (small in magnitude) and cardiorespiratory
(moderate in magnitude) fitness outcomes in persons with MS. Such an indication
of magnitude is important for clinical research and practice by providing an
evidence-based estimate of the actual benefit that exercise training confers on
physiological fitness.
CI - Copyright (c) 2016 American Congress of Rehabilitation Medicine. Published by
Elsevier Inc. All rights reserved.

Langue : ANGLAIS