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First-line therapy in relapsing remitting multiple sclerosis

BIOTTI D; CIRON J
REV NEUROL (Paris) , 2018, vol. 174, n° 6, p. 419-428
Doc n°: 187660
Localisation : Documentation IRR

D.O.I. : http://dx.doi.org/DOI:10.1016/j.neurol.2018.03.012
Descripteurs : AE3 - SEP

Today, first-line treatments for multiple sclerosis include injectable
immunomodulators - some of which have been on the market for nearly 25 years - as
well as teriflunomide and dimethyl fumarate, which are more recent, but have
opened the way for oral treatments. These drugs are considered similar in
effectiveness, and their safety and side-effect profiles are generally
reassuring. These treatments have been associated with a reduction in
radiological and clinical disease activity, and a positive effect on patient
quality of life, especially when introduced early in the disease process. This
article will discuss data on first-line treatments currently available in France,
their effectiveness and safety, and their place in pediatric patients and in woman who plan to become pregnant.
CI - Copyright (c) 2018 Elsevier Masson SAS. All rights reserved.

Langue : ANGLAIS

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