Article

AIM: To assess outcome after neonatal perforator stroke in the largest cohort to
date. METHOD: Survivors from a cohort of children diagnosed with neonatal
perforator stroke using cranial ultrasound or magnetic resonance imaging were
eligible for inclusion. Recovery and Recurrence Questionnaire score, presence of
cerebral palsy (CP), and crude outcome were assessed, specifically (1) the
ability to walk independently, (2) participation in regular education, and (3)
the presence of epilepsy. RESULTS: Thirty-seven patients (20 males, 17 females)
aged 3 to 14 years (mean age 8y) were included in the study:
14 with isolated
single perforator stroke, four with multiple isolated perforator strokes, and 19
with additional brain injury.
Out of 18 children with isolated perforator
stroke(s), four had CP, one could not walk independently, and one developed
epilepsy. The posterior limb of the internal capsule was involved in four out of
18 patients; three of these patients had CP. Of 19 children with additional brain
injury, 11 had CP and three were not able to walk independently. Three out of
nine children with concomitant cortical middle cerebral artery stroke developed
epilepsy. INTERPRETATION: Perforator stroke patterns can be of use in predicting
long-term outcome and for guiding counselling and surveillance. Motor outcome was
favourable in children with isolated perforator stroke(s), except when the
posterior limb of the internal capsule was involved.
CI - (c) 2015 Mac Keith Press.

Langue : ANGLAIS