Article

OBJECTIVES: To assess the prevalence and risk of stroke among adults with polio
and controls. DESIGN:
A prospective, probability-sampling, 6-year
population-based cohort study. SETTING: A National Health Insurance Research
Database consisting of 316,355 randomly selected enrollees.
The database is
related to a National Health Insurance program with more than 22 million
participants. PARTICIPANTS: After excluding patients under 40 years of age, polio
patients (N=212) (mean age +/- SD, 54.0+/-10.2 y; 57.1% men) were identified from
the database from January 1, 2003 to December 31, 2008. For each polio patient, 2
age- and sex-matched patients were recruited as controls. Control patients did
not have any neuromuscular diseases commonly found in childhood. The frequencies
of patients with potential risk factors for stroke were assessed. INTERVENTION:
None. MAIN OUTCOME MEASURE: The prevalence and the adjusted odds ratio of
ischemic stroke among polio patients and the controls were estimated. RESULTS:
Polio patients had a higher prevalence of stroke (10.8% vs 2.4%, P<.001) than the
controls. Polio patients with hypertension had a much higher prevalence of stroke
(23.0%). The risk of stroke was higher for polio patients compared with the
controls, yielding an adjusted odds ratio of 4.17 (95% confidence interval,
1.84-9.45, P<.001). Polio was a significant risk factor for stroke independent
from hypertension, diabetes mellitus, hyperlipidemia, and cardiac diseases.
CONCLUSIONS: Adults with polio had a high prevalence of ischemic stroke. Polio
was an additional risk factor for stroke. Polio patients with hypertension might
potentiate the risk of stroke. Developing a health promotion program, suitable
for polio patients, to increase participation in activities and exercises may be
essential, especially for polio patients with hypertension.
CI - Copyright (c) 2012 American Congress of Rehabilitation Medicine. Published by
Elsevier Inc. All rights reserved.

Langue : ANGLAIS