Article

OBJECTIVES: To compare the reciprocal control of agonist and antagonist muscles
in individuals with and without spinocerebellar ataxia (SCA) and to evaluate the
effect of a 4-week leg cycling regimen on functional coordination and reciprocal
control of agonist and antagonist muscles in patients with SCA. DESIGN:
Randomized controlled trial with repeated measures.
SETTING: Research laboratory
in a general hospital. PARTICIPANTS: Individuals with SCA (n=20) and without SCA
(n=20). INTERVENTIONS: A single 15-minute session of leg cycling and a 4-week
cycling regimen. MAIN OUTCOME MEASURES: Individuals with SCA (n=20) and without
SCA (n=20) underwent disynaptic reciprocal inhibition and D1 inhibition tests of
the soleus muscles before and after a single 15-minute cycling session.
Individuals with SCA were randomly assigned to either participate in 4 weeks of
cycling training (n=10) or to receive no training (n=10). The disynaptic
reciprocal inhibition and D1 inhibition and International Cooperative Ataxia
Rating Scale (ICARS) scores were evaluated in both groups after 4 weeks. RESULTS:
Individuals with SCA showed abnormally strong resting values of disynaptic
reciprocal inhibition and D1 inhibition (P<.001) and impaired inhibition
modulation capacity after a single 15-minute session of cycling (P<.001). The
inhibition modulation capacity was restored (P<.001), and the ICARS scores
improved significantly (pre: 13.5+/-9.81, post: 11.3+/-8.74; P=.046) after 4
weeks of cycling training. CONCLUSIONS: A 4-week cycling regimen can normalize
the modulation of reciprocal inhibition and functional performance in individuals
with SCA. These findings are applicable to the coordination training of patients.
CI - Copyright (c) 2015 American Congress of Rehabilitation Medicine. Published by
Elsevier Inc. All rights reserved.

Langue : ANGLAIS