Article

OBJECTIVE: To investigate the effects of arm-cranking exercise training on
plasminogen activator inhibitor 1 (PAI-1) as a risk factor of deep vein
thrombosis, along with general physical parameters such as muscle strength,
aerobic capacity, and hemodynamics, in individuals with spinal cord injury (SCI)
and control subjects.
DESIGN: Longitudinal study.
SETTING: Community-based
supervised intervention. PARTICIPANTS: Participants (N=17) comprised individuals
with SCI (n=9) who volunteered for this study, and able-bodied individuals (n=8)
matched for age, height, and body mass index who were assessed at baseline only.
INTERVENTION: The arm-cranking exercise program was performed for 10 weeks with 4
sessions per week. Sessions consisted of 2 sets of warmup (5min) and arm crank
exercises (25min) with a 10-minute recovery at an intensity of 50% to 70% of
heart rate reserve. MAIN OUTCOME MEASURES: Body mass (BM), waist circumference
(WC), aerobic capacity (peak oxygen consumption [Vo2peak]), PAI-1, blood
pressure, glucose metabolism, and lipids. RESULTS: PAI-1, BM, WC, systolic blood
pressure, and triglycerides (TG) decreased, and Vo2peak increased after training
(P<.05, respectively). Spearman rank-order analysis revealed that changes in
PAI-1 were related to changes in Vo2peak, BM, WC, TG, and high-density
lipoprotein cholesterol. Multiple linear regression analysis revealed that WC was
the most sensitive factor for predicting changes in PAI-1 (P=.038). CONCLUSIONS:
These results suggest that 10 weeks of arm-cranking exercise training for people
with SCI may help to reduce the risk factors of cardiovascular disease. In
addition, changes in abdominal fat may be related to changes in PAI-1 in the SCI population.
CI - Copyright (c) 2017 American Congress of Rehabilitation Medicine. Published by
Elsevier Inc. All rights reserved.

Langue : ANGLAIS