Article

Objective : To investigate whether poor response to exercise training can detect restenosis in asymptomatic patients after percutaneous transluminal coronary angioplasty (PTCA). Design: Case-control study. Setting: A hospital-based outpatient cardiac rehabilitation program in Taiwan. Participants: Sixteen patients aged 49.7+/-7.8 years who had undergone PTCA and completed a 3-month exercise program. Patients were separated into a restenosis group (n=7; age, 46.4+/-9.8y) and a nortrestenosis group (n=9; age, 52.3+/-12.9y), according to their angiography follow-up results. The interval between PTCA and angiography ranged from 6 months to 2 years. Intervention: Bicycle exercise workouts were conducted 3 times a week during rehabilitation, with exercise intensity adjusted to each patient's ventilatory threshold. Main Outcome Measures: A graded exercise test with gas analysis was conducted before training, at 6 weeks and at 3 months after training, to evaluate the sequential changes of cardiorespiratory function. Results: After 3 months of training, the nonrestenosis group showed an increase of 30.4% in peak oxygen uptake (VO(2)peak, P<.05) 13.7% in peak oxygen pulse (P<.05), 22.2% in peak rate-pressure product (P<.05), and 13.6% in peak work rate (P<.05). Most of the improvement occurred within the first 6 weeks of training. The restenosis group did not show significant increase in these variables. At the ventilatory threshold, the nonrestenosis group also displayed a significant increase of (V)over dotO(2) oxygen pulse, and work rate. However, the restenosis group showed no improvement after training. Conclusion: Functional recovery appears to be a good indicator of restenosis for patients after PTCA. A poor response to exercise can be noted within 6 weeks of training in PTCA patients with restenosis.

Langue : ANGLAIS

Identifiant basis : 2003227870