Article

OBJECTIVE: To test the hypothesis that combined aerobic and resistance training
and non-invasive ventilatory support result in additional benefits compared with
combined aerobic and resistance training alone in heart failure patients. DESIGN:
A randomized, single-blind, controlled study. SETTING: Cardiac rehabilitation
center. PARTICIPANTS:
A total of 46 patients with New York Heart Association
class II/III heart failure were randomly assigned to a 10-week program of
combined aerobic and resistance training, plus non-invasive ventilatory support (
n = 23) or combined aerobic and resistance training alone ( n = 23). METHODS:
Before and after intervention, results for the following were obtained: 6-minute
walk test, forced vital capacity, forced expiratory volume at one second, maximal
inspiratory muscle pressure, and maximal expiratory muscle pressure, with
evaluation of dyspnea by the London Chest Activity of Daily Living scale, and
quality of life with the Minnesota Living With Heart Failure questionnaire.
RESULTS: Of the 46 included patients, 40 completed the protocol. The combined
aerobic and resistance training plus non-invasive ventilatory support, as
compared with combined aerobic and resistance training alone, resulted in
significantly greater benefit for dyspnea (mean change: 4.8 vs. 1.3, p = 0.004),
and quality of life (mean change: 19.3 vs. 6.8, p = 0.017 ). In both groups, the
6-minute walk test improved significantly (mean change: 45.7 vs. 44.1, p =
0.924), but without a statistically significant difference. CONCLUSION:
Non-invasive ventilatory support combined with combined aerobic and resistance
training provides additional benefits for dyspnea and quality of life in moderate
heart failure patients.
TRIAL REGISTRATION: ClinicalTrials.gov identifier:
NCT02384798. Registered 03 April 2015.

Langue : ANGLAIS