Article

The purpose of this systematic review was to provide an up-to-date global
overview of the separate prevalences of motor and cognitive delays and cerebral
palsy (CP) in very preterm (VPT) and very-low-birthweight (VLBW) infants. METHOD:
A comprehensive search was conducted across four databases. Cohort studies
reporting the prevalence of CP and motor or cognitive outcome from 18 months
corrected age until 6 years of VPT or VLBW infants born after 2006 were included.
Pooled prevalences were calculated with random-effects models. RESULTS: Thirty
studies were retained, which included a total of 10 293 infants. The pooled
prevalence of cognitive and motor delays, evaluated with developmental tests, was
estimated at 16.9% (95% confidence interval [CI] 10.4-26.3) and 20.6% (95% CI
13.9-29.4%) respectively. Mild delays were more frequent than moderate-to-severe
delays. Pooled prevalence of CP was estimated to be 6.8% (95% CI 5.5-8.4).
Decreasing gestational age and birthweight resulted in higher prevalences. Lower
pooled prevalences were found with the Third Edition of the Bayley Scales of
Infant Development than with the Second Edition. INTERPRETATION: Even though
neonatal intensive care has improved over recent decades, there is still a wide
range of neurodevelopmental disabilities resulting from VPT and VLBW births.
However, pooled prevalences of CP have diminished over the years. WHAT THIS PAPER
ADDS: The Bayley Scales of Infant and Toddler Development, Third Edition reported
lower pooled prevalences of motor and cognitive delays than the Second Edition.
The pooled prevalence of cerebral palsy in infants born extremely preterm was
reduced compared with previous meta-analyses.
CI - (c) 2018 Mac Keith Press.

Langue : ANGLAIS