Article

OBJECTIVE: To review the evidence concerning the effects of postoperative
exercise interventions on exercise capacity and health-related quality of life
following resection for non-small cell lung cancer, and to review whether
different initiation times of exercise produce different effects on exercise capacity. DATA SOURCES: Comprehensive literature search of MEDLINE, Embase, CENTRAL, CINAHL and PEDro. STUDY SELECTION: Randomized controlled trials
examining the effects of exercise interventions were eligible for inclusion. DATA
EXTRACTION: Postoperative outcome measurements were extracted and the quality of
evidence was graded using Grading of Recommendations Assessment, Development and
Evaluation (GRADE) Working Group. DATA SYNTHESIS: Four randomized controlled
trials were identified involving 262 participants. Short-term follow-up (12-20
weeks) showed significantly higher exercise capacity and physical component of
health-related quality of life in the intervention group (standardized mean
difference (SMD) 0.48; 95% confidence interval (CI) 0.04-0.93) compared with the
control group (SMD 0.50; 95% CI 0.19-0.82). There was no difference between the
effect of late- and early-initiated exercise intervention. CONCLUSION: Exercise
has a small-to-moderate effect at short-term follow-up on exercise capacity and
the physical component of health-related quality of life in patients operated for
lung cancer. The long-term effects of exercise capacity are unknown.
Early-initiated exercise programmes (2 weeks post-operation) did not show an
effect on exercise capacity. These findings should be interpreted with caution.

Langue : ANGLAIS