Article

Dépistage des troubles cognitifs dans la maladie de Parkinson Abstract : Cognitive screening is crucial in Parkinson's disease (PD). However,
there is still a lack of short tools in French. In this study,
we aimed to
compare the Parkinson Neuropsychometric Dementia Assessment (PANDA) with the Mini Mental Parkinson (MMP),
the Mini Mental State Examination (MMSE) and the Clock
Test in French-speaking patients. We also aimed to propose cut-off scores for
cognitive impairment and dementia for the French language version of the PANDA.
METHOD: Fifty-one patients with PD took the PANDA, the MMSE, the MMP, and the
Clock Test. They also underwent extensive neuropsychological testing by a
neuropsychologist who was blinded to the above-mentioned screening test results.
Patients were classified as either having normal cognition (n=15), mild cognitive
impairment (n=20) or dementia (n=16). RESULTS: When compared with the three other
screening tools, the PANDA exhibited the highest area under the curve (AUC) for
both cognitive disorders and dementia. Using the cut-off scores proposed for the
German version, the PANDA had 94% specificity and 100% sensitivity for dementia
and 100% and 72%, respectively for cognitive disorders. CONCLUSIONS: In our
study, the PANDA exhibited a higher discriminative power than the three other
tests in detecting cognitive disorders and dementia.
In PD patients, the PANDA
should thus be considered for the detection of cognitive impairment in routine
clinical practice.
CI - Copyright (c) 2015 Elsevier Masson SAS. All rights reserved.

Langue : ANGLAIS