Article

Objective: To evaluate prognosis and recovery in patients with locked-in syndrome (LIS) receiving early intensive rehabilitative care. Design: Consecutive sample and follow-up for 5 months to 6 years. Setting: Three rehabilitation centers in Italy. Participants: Fourteen patients with LIS who underwent the same treatment and subsequently recovered. Interventions: Intensive nursing care and intensive and early rehabilitative program, including physiotherapy and respiratory, swallowing, and speech training. For 4 patients, occupational therapy was performed; 4 subjects also had oculomotor training. After discharge, rehabilitative maintenance care continued for each patient. Main Outcome Measures: Motor recovery according to the Patterson and Grabois classification, functional improvement, and mortality rate. Results: A significant motor recovery was found in 21% of subjects, within 3 to 6 months of onset of the morbid event; complete swallow recovery in 42%; verbal communication in 28%; communication through devices in 42%; effective bladder and bowel control in 35%; and good breathing patterns in 50%. At follow-up, the mortality rate was 14% and only 2 complications were reported. Conclusions: Intensive and early rehabilitation, begun within about 1 month of the morbid event, improved the functional recovery and reduced the mortality rate, which, as reported in the literature, had been 60% about 10 years ago. Further studies are necessary to confirm these data.

Langue : ANGLAIS

Identifiant basis : 2003227367