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(1) H-MR spectroscopy is sensitive to subtle effects of perinatal asphyxia
MANERU C; JUNQUE C; BARGALLO N
NEUROLOGY , 2001, vol. 57, n° 6, p. 1115-1118 Doc n°: 103150 Localisation : Documentation IRR Descripteurs : AJ11 - DEVELOPPEMENT DU SYSTEME NERVEUX The authors performed neuropsychological and (1)H-MRS studies in 18 subclinical patients with antecedents of perinatal asphyxia (PA) and in 18 matched control subjects. Patients with PA showed reduced values of N-acetylaspartate (NAA) in both the basal ganglia and the midtemporal region (MTR) and reduced NAA/choline values in the MTR. Neuropsychological testing showed group differences in tasks related to attention and memory. These results indicate persistent dysfunctions in cerebral structures vulnerable to hypoxia and demonstrate the utility of MRS for the long-term evaluation of cerebral sequelae of neonatal asphyxia Langue : ANGLAIS Tiré à part : OUI Identifiant basis : 2002218982 |
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