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Interferon-beta for treatment of rheumatoid arthritis ?
VANHOLTEN J; PLATERZYBERK C; TAK PP
ARTHRITIS RES , 2002, vol. 4, n° 6, p. 346-352 Doc n°: 106992 Localisation : Documentation IRR Descripteurs : DA6 - TRAITEMENTS - APPAREIL LOCOMOTEUR IFN-beta treatment is emerging as a potentially effective form of therapy in various immune-mediated conditions. The present review addresses the possible role of IFN-beta in immune-mediated diseases such as multiple sclerosis and rheumatoid arthritis. Several placebo-controlled trials are discussed, as are the available immunological data that are relevant to this field. Review of these data provides evidence that IFN-beta has some beneficial therapeutic effect in patients with relapsing-remitting multiple sclerosis and might also have antirheumatic potential. This notion is supported by recent studies showing a critical role for IFN-beta in bone homeostasis. Langue : ANGLAIS Tiré à part : OUI Identifiant basis : 2003225073 |
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