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Stress echocardiography for risk stratification of patients with chest pain and normal or slightly narrowed coronary arteries
BIGI R; CORTIGIANI L; BAX JJ
J AM SOC ECHOCARDIOGR , 2002, vol. 15, n° 10, p. 1285-1289 Doc n°: 107420 Localisation : Documentation IRR Descripteurs : FA331 - MALADIE CORONARIENNE One hundred twenty-five patients (60 10 years old, 60 women) with known (35, previous myocardial infarction) or suspected (90) coronary artery disease (CAD) and no more than 50% coronary stenoses underwent pharmacologic (48 dipyridamole and 77 dobutamine) stress echocardiography (SE) and prospective follow-up (36 22 months) for cardiac death, nonfatal infarction, and unstable angina. The ability of clinical and SE variables to predict the outcome was assessed by the Cox model. A significant increase in the global chi-square of the model indicated an incremental prognostic value. Nine events occurred: 2 fatal and 5 nonfatal infarctions; and 2 hospitalizations for unstable angina. Hypertension, positive SE, and peak wall motion score index were multivariate predictors of outcome, but SE provided an 87.5% increase in the global chi-square (P < .001). Patients with positive SE had a significantly lower event-free survival compared with those with negative SE. Therefore, we conclude that SE provides incremental prognostic information in patients with chest pain without critical coronary artery disease. Langue : ANGLAIS Tiré à part : OUI Identifiant basis : 2003225501 |
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