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Repeated sessions of noninvasive brain DC stimulation is associated with motor function improvement in stroke patients
BOGGIO PS; NUNES A; RIGONATTI SP; NITSCHE MA; PASCUAL LEONE A; FREGNI F
RESTOR NEUROL NEUROSCI , 2007, vol. 25, p. 123-129 Doc n°: 143864 Localisation : Documentation IRR Descripteurs : AF21 - ACCIDENTS VASCULAIRES CEREBRAUX Recent evidence has suggested that a simple technique of noninvasive brain stimulation - transcranial direct current stimulation (tDCS) - is associated with a significant motor function improvement in stroke patients. METHODS: We tested the motor performance improvement in stroke patients following 4 weekly sessions of sham, anodal- and cathodal tDCS (experiment 1) and the effects of 5 consecutive daily sessions of cathodal tDCS (experiment 2). A blinded rater evaluated motor function using the Jebsen-Taylor Hand Function Test. RESULTS: There was a significant main effect of stimulation condition (p=0.009) in experiment 1. Furthermore there was a significant motor function improvement after either cathodal tDCS of the unaffected hemisphere (p=0.016) or anodal tDCS of the affected hemisphere (p=0.046) when compared to sham tDCS. There was no cumulative effect associated with weekly sessions of tDCS, however consecutive daily sessions of tDCS (experiment 2) were associated with a significant effect on time (p< 0.0001) that lasted for 2 weeks after treatment. CONCLUSIONS: Langue : ANGLAIS Tiré à part : OUI |
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