Article

The objective was to establish the extent to which physical functioning capacity
and self-report measures are able to predict the habitual walking performance in
ambulatory persons with multiple sclerosis. Fifty persons with multiple sclerosis
(Expanded Disability Status Scale, EDSS, 1.5-6.5) were tested on leg muscle
strength as well as walking and balance capacity, and completed self-report
indices on perceived physical functioning. Habitual walking performance, that is,
the real amount of steps that is performed in the customary living environment,
was registered by means of an ambulant accelerometer-based monitor during seven
consecutive days. Mild (EDSS 1.5-4.0, n = 29) and moderate (EDSS 4.5-6.5, n = 21)
multiple sclerosis subgroups were additionally distinguished as predictor
variables and values were hypothesized to differ depending on multiple sclerosis
severity and concomitant ambulatory function. Multiple regression analyses
yielded a single most significant predictor for each (sub)group with other
variables making no independent contribution to the variation in habitual walking
performance. For the total study sample, this was the 6-Minute Walking Test (R(2)
= 0.458, p < 0.01). In the mild multiple sclerosis subgroup, the 6-Minute Walking
Test was again most predictive, yet to a modest degree (R(2) = 0. 187, p = 0.02).
In the moderate multiple sclerosis subgroup, the 2-Minute Walking Test explained
over half of the variance (R(2) = 0.532, p < 0.01). Habitual walking performance
is best reflected by longer walking capacity tests. The extent to which it can be
predicted based on clinical testing is larger in a multiple sclerosis patient
sample with more severe walking disability. Ambulatory monitoring, however,
includes aspects of community ambulation not captured in the clinic, and must be
considered as an additional outcome for evaluating interventions in multiple
sclerosis.

Langue : ANGLAIS

Tiré à part : OUI