Article

OBJECTIVE: To investigate the long-term effect of expanded cardiac rehabilitation
on a composite end-point, consisting of cardiovascular death, myocardial
infarction or readmission for cardiovascular disease, in patients with coronary
artery disease. Single-centre prospective randomized controlled trial.
University hospital. Two hundred and twenty-four patients with
acute myocardial infarction or undergoing coronary artery by-pass grafting.
Patients were randomized to expanded cardiac rehabilitation (a
one-year stress management programme, increased physical training, staying at a
'patient hotel' for five days after the event, and cooking sessions), or to
standard cardiac rehabilitation. MAIN MEASURES: Data on cardiovascular death,
myocardial infarction, readmission for cardiovascular disease and days at
hospital for cardiovascular reasons were obtained from national registries of the
Swedish National Board of Health and Welfare. RESULTS: The primary end-point
occurred in 121 patients altogether (54%). The number of cardiovascular events
were reduced in the expanded rehabilitation group compared with the standard
cardiac rehabilitation (53 patients (47.7%) versus 68 patients (60.2%); hazard
ratio 0.69; P =0.049). This was mainly because of a reduction of myocardial
infarctions in the expanded rehabilitation group. During the five years 12
patients (10.8%) versus 23 patients (20.3%); hazard ratio 0.47; P =0.047 had a
myocardial infarction. Days at hospital for cardiovascular reasons were
significantly reduced in patients who received expanded cardiac rehabilitation
(median 6 days) compared with standard cardiac rehabilitation (median 10 days; P = 0.02). CONCLUSION: Expanded cardiac rehabilitation after acute myocardial
infarction or coronary artery bypass grafting reduces cardiovascular morbidity
and days at hospital for cardiovascular reasons.

Langue : ANGLAIS