Article

Neocortical development represents more than a simple unfolding of a genetic
blueprint: rather, it represents a complex dance of genetic and environmental
events that interact to adapt the brain to fit a particular environmental
context. Most cortical regions are sensitive to a wide range of experiential
factors during development and later in life, but the injured cortex appears to
be unusually sensitive to perinatal experiences. This paper reviews the factors
that influence how normal and injured brains (both focal and ischemic injuries)
develop and adapt into adulthood. Such factors include prenatal experiences in
utero as well as postnatal experiences throughout life. Examples include the
effects of sensory and motor stimulation, psychoactive drugs (including illicit
and prescription drugs), maternal and postnatal stress, neurotrophic factors, and
pre- and postnatal diet. All these factors influence cerebral development and
influence recovery from brain injury during development.
CI - (c) The Authors. Developmental Medicine & Child Neurology (c) 2011 Mac Keith
Press.

Langue : ANGLAIS