Article

This article addresses the pathophysiology, diagnostic approaches, and
therapeutic options in the more common forms of muscular dystrophy, especially
those seen in pediatric and young adult populations. The major emphasis is on the
dystrophinopathies because their treatment options are templates for those used
in various other forms of dystrophy. Most patients with cardiomyopathy are
treated with angiotensin-converting enzyme inhibitors or angiotensin receptor
blockers, with other agents added as the disease progresses. Destination
therapies and transplantation options are mentioned where appropriate. Some
dystrophies can have significant conduction abnormalities requiring pacemaker
treatment. Others with ventricular tachydysrhythmias may necessitate internal
cardiac defibrillator placement.
CI - Copyright (c) 2012 Elsevier Inc. All rights reserved.

Langue : ANGLAIS