Article

Rééducation fondée sur les preuves. Sound rigorous methods are needed by researchers and providers to address
practical questions about risks, benefits, and costs of interventions as they occur in routine clinical practice such as : Are treatments used in daily practice associated with intended outcomes ? For whom does an intervention work best ?
With limited clinical resources, what are the best interventions to use for specific types of patients ? Answers to such questions can help clinicians, patients,
researchers, and health care administrators learn from, and improve, real-world
everyday clinical practice. In this article, we describe existing research
designs to demonstrate clinical usefulness and comparative effectiveness of
rehabilitation treatments. We compare randomized controlled trials and
observational cohort studies of various types, including those that use
instrumental variables or propensity scores to control for potential patient or
treatment selection effects.
We argue that practice-based evidence (PBE) study
designs include features that address limitations inherent in both randomized
trials and traditional observational studies, and also reduce the need for
instrumental variables and propensity scores methods. We give examples of how PBE
designs have been used in various rehabilitation areas to determine better
treatments for specific types of patients.
CI - Copyright (c) 2012 American Congress of Rehabilitation Medicine. Published by
Elsevier Inc. All rights reserved.

Langue : ANGLAIS