Article

Metabolic diseases constitute a frequent etiologic group of axonal and
small-fiber neuropathies. Recent works in this field are dominated by diabetic
neuropathy (clinical presentation, prognostic factors) because of its prevalence.
Vitamin B12 deficiency aroused several studies in 2011.
This renewed interest for
this well known entity ensues from the lack of sensibility of its biological
markers underestimating its prevalence, its clinical spectrum and therefore,
access to its therapy. Finally, 2011 highlighted the growing interest of the
measure of the intra-epidermic nerve fibers density by skin biopsy for some
metabolic disorders such as infra-clinical hypothyroidism, chronic renal failure
or Fabry disease.
CI - Copyright (c) 2012 Elsevier Masson SAS. All rights reserved.

Langue : FRANCAIS