Article

Responsiveness and agitation are common targets for pharmaceutical intervention
after traumatic brain injury (TBI) in children. This focused review presents a
critical discussion of the limited literature available on the use of medications
for disorders of consciousness and agitation in children with TBI. For disorders
of consciousness, evidence from several small studies supports a potential
benefit of dopaminergic agents for improving responsiveness in some children with
lower levels of function after TBI. Larger studies, likely requiring multicenter
collaborations, are needed to more definitively address questions regarding the
use of medications for responsiveness in children with TBI. The literature
regarding use of pharmaceutical agents for agitation in children with TBI is even
more limited. The dearth of literature regarding the effects of medications used
for agitation in children with TBI highlights the need for additional basic and
clinical science contributions in this area.
CI - Copyright (c) 2013 American Academy of Physical Medicine and Rehabilitation.
Published by Elsevier Inc. All rights reserved.

Langue : ANGLAIS