Article

Repetitive transcranial magnetic stimulation (rTMS) has emerged as a
potential therapeutic tool for the rehabilitation of language in chronic
non-fluent aphasia post-stroke. Previous studies report that low frequency (1 Hz)
rTMS applied to homologous language sites can facilitate behavioural language
changes. Improvements in picture naming performance and speech output are
frequently reported. OBJECTIVES: This study aims to assess the efficacy of
inhibitory rTMS to modulate language performance in non-fluent aphasia. METHODS:
Low-frequency (1 Hz) rTMS was applied to six active stimulation and six placebo
patients for 20 min per day over 10 days, as outlined in a previous published
investigation. Behavioural language outcome measures were taken at baseline
(pre-stimulation) and 1 week, 2 months, 8 months and 12 months post-stimulation.
RESULTS: The findings demonstrate treatment-related changes observed in the
stimulation group, up to 12 months post-stimulation, when compared to the placebo
control group over time for naming performance, expressive language and auditory
comprehension. CONCLUSION: These outcomes provide considerable evidence to
support the theory of rTMS modulating mechanisms of transcallosal disinhibition
in the aphasic brain, and highlight the potential clinical application of rTMS
for language rehabilitation in chronic aphasia.

Langue : ANGLAIS