Article

The objective of this study was to describe a cohort of infants with basal
ganglia stroke associated with mineralization in the lenticulostriate arteries
and their clinical outcomes. METHOD: Subcortical strokes occurring in infants
during the study period were categorized as arterial ischaemic, venous, or
haemorrhagic. A cohort of infants with basal ganglia infarcts and associated
mineralization of lenticulostriate arteries were identified. This group was
analysed for possible aetiological factors, clinical course, and recurrence rate
of the stroke. RESULTS: Of 23 infants with basal ganglia arterial ischaemic
stroke, 22 (16 males, six females; mean age 11mo [+/-SD 4.8mo]) were found to
have lenticulostriate artery mineralization. Twenty infants presented with
hemiparesis and two presented with recurrent episodes of hemidystonia. Eighteen
infants had a history of minor trauma before onset of stroke. No other
predisposing factors were identified in this cohort. There were no demonstrable
causes for vascular and soft tissue calcification. The mean follow-up was 11
months, during which five infants experienced stroke recurrence. Of the 17
infants who did not experience a recurrent stroke, eight exhibited complete
neurological recovery, and nine had mild residual hemiparesis. INTERPRETATION:
Acute basal ganglia stroke after minor trauma associated with mineralization of
lenticulostriate arteries in infants is a distinct clinicoradiological entity.
Investigations for prothrombotic states and vasculopathies are normal. Although
neurological outcomes in most children are good, trauma is a risk factor for
recurrence of stroke.
CI - (c) 2013 Mac Keith Press.

Langue : ANGLAIS