Article

Exercise-induced pulmonary arterial hypertension (EIPAH) is
associated with reduced exercise capacity and abnormal central haemodynamic
responses to maximal aerobic exercise. Aerobic and resistance exercise training
are commonly employed to treat reduced exercise capacity; however, the
haemodynamic response to aerobic and resistance exercise, at training
intensities, in subjects with EIPAH is unknown. METHODS: Fourteen subjects (11
with scleroderma, 12 females) with EIPAH underwent cardiopulmonary exercise
testing on a cycle ergometer, a one-repetition maximum (1RM) strength test and
resistance exercise at 40% and 60% of maximum on a bilateral leg press machine.
All tests were performed with a pulmonary artery catheter in situ. Haemodynamic
and symptomatic responses to aerobic and resistance exercise, performed at 40% of
peak oxygen consumption and 40% of 1RM, and at 60% of peak oxygen consumption and
60% of 1RM, were compared. For maximal exercise, the highest haemodynamic
responses recorded during the cycling and 1RM tests were compared. RESULTS: There
were no differences in haemodynamic or symptomatic responses between the two
modalities of submaximal exercise. At maximal exercise, all haemodynamic and
symptomatic responses were lower during resistance compared with aerobic exercise
(p < 0.05). CONCLUSIONS: At the intensities studied, lower-limb resistance
exercise was well tolerated and was mostly associated with similar or lower
haemodynamic responses compared with aerobic exercise, in subjects with EIPAH.

Langue : ANGLAIS