Article

Executive functions is an umbrella term describing a wide range of higher order
processes that allow the flexible modification of thought and behaviour in
response to changing cognitive or environmental contexts. Impairment of executive
functions is common in neurodegenerative disorders such as Alzheimer's disease.
These deficits negatively affect everyday activities and hamper the ability to
cope with other cognitive or behavioural disorders. In this paper, we propose a
synthesis of the knowledge on executive impairments in clinical and preclinical
Alzheimer's disease, mostly leaning on the current studies made in this domain.
We made some propositions for neuropsychological assessment of executive
functions in preclinical and clinical phases of Alzheimer's disease. We hope that
this overview will provide a useful insight into an area that is still
insufficiently explored in the field of the neuropsychology of Alzheimer's
disease.
CI - Copyright (c) 2013 Elsevier Masson SAS. All rights reserved.

Langue : ANGLAIS