Article

Neuroimaging studies in stroke patients provide substantial evidence
for the involvement of widespread cortical and subcortical regions in the control
of swallowing. Although the affective network and the default mode network are
functionally related to "autonomic" and "volitional" swallowing, little is known
about their functional changes in dysphagic stroke patients. METHODS: Unbiased
seeds functional connectivity analysis was used to study the connectivity
patterns of these resting-state networks. Resting-state functional magnetic
resonance imaging was performed in stroke patients with (n = 12) and without
dysphagia (n = 12). RESULTS: Compared with healthy controls, stroke patients with
and without dysphagia had decreased functional connectivity in the default mode
network and the affective network. Moreover, stroke patients with dysphagia also
had decreased functional connectivity in both the default mode network and the
affective network relative to patients without dysphagia. CONCLUSION:
The difference in the extent of impairment in the default mode network and affective
network of stroke patients with and without dysphagia may lead to improved
understanding of the neuropathophysiological mechanism and rehabilitation of
dysphagia.

Langue : ANGLAIS