Article

OBJECTIVE: To conduct a systematic review and meta-analysis on the efficacy of
oral non-steroidal anti-inflammatory drugs for rotator cuff tendinopathy. DESIGN:
Systematic review. METHOD: A literature search was conducted in 4 databases for
randomized controlled trials published until 05/2013, comparing the efficacy of
oral anti-inflammatory drugs to any other intervention. Studies characteristics
were extracted using a standardized form and the methodological quality was
evaluated. Results were summarized qualitatively or quantitatively. RESULTS: The
mean methodological score of the 12 included studies was 53.6 +/- 8.8%. The
majority of studies included acute cases and were underpowered to detect
differences in adverse events. Compared to a placebo, oral non-steroidal
anti-inflammatory drugs were found to provide short-term pain relief (pooled mean
difference: -2.69; 95% confidence interval: -1.96 to -3.41) but not function.
Oral anti-inflammatory- drugs and corticosteroids injections have similar
short-term efficacy in terms of pain reduction as well as in function (pooled
standardized mean difference: 0.09; 95% confidence interval: -0.25 to 0.44).
CONCLUSION: Low to moderate grade evidence exists regarding the efficacy of
non-steroidal anti-inflammatory drugs for rotator cuff tendinopathy. Oral
anti-inflammatory drugs are effective in reducing short-term pain but not
function. In terms of pain and function, oral anti-inflammatory drugs in the
short term are as effective as corticosteroid injections.

Langue : ANGLAIS